Description
Description:
A clear solution of pale yellow color.
Composition
100 ml of the preparation contain
active ingredients :
Calcium gluconate 32.82 grams;
Calcium glycerophosphate 8.13 grams;
Magnesium chloride 4.18 grams.
Pharmacological properties:
Calcium is an important mineral that forms hydroxyapatite crystals in bones, which gives them strength. Calcium ions regulate the permeability of biological membranes, providing neuromuscular conduction. Deficiency of calcium ions and tissue fluids increases the excitability of nerve nodes, which can lead to tetany. In addition, calcium affects the colloidal state of proteins by reducing their dispersion, which leads to a decrease in the permeability of blood vessels. Calcium stimulates the cardiovascular system and, when administered intravenously, a nice part of the autonomic nervous system, increasing the release of adrenaline; available in the process of blood coagulation.
Phosphorus together with calcium affects the development of bones and teeth; It is part of phospholipids, phosphoprotein, nucleic acids and many coenzymes. Inorganic primary and secondary phosphates affect the support of acid-base balance, play an important role in the metabolism of carbohydrates. Adenosine triphosphate is involved in the accumulation and transformation of energy in the body.
Magnesium is an important intracellular ion necessary for the activation of many enzymes, in particular those that are involved in the conservation of energy in the form of phosphate compounds. Magnesium regulates the release of acetylcholine from the motor end plates, affects muscle excitability.
Application:
Treatment and prevention of animal diseases that are associated with metabolic disorders of calcium, phosphorus and magnesium:
– hypocalcemia (postpartum paresis, rickets in young animals, osteomalacia in old animals);
– various forms of tetany (transport and pasture tetany, tetany during pregnancy and lactation);
– allergy, toxicosis, postpartum hemoglobinuria, spotted disease, urticaria, exanthema, hemorrhagic diathesis, hematuria and myoglobinuria;
– paresis due to a deficiency of calcium or phosphorus of various etiologies;
– auxiliary therapy for poisoning with lead, fluorine or oxalic acid.
Dosage:
The drug is administered intravenously, internally, and at times doses:
Kind of animal | Dose of the drug, ml | Route of administration |
Horses weighing 660 lb (500 kg) | 80-100 | Intravenously |
Cattle weighing 660 lb (500 kg) | 80-100 | Intravenously, intramuscularly or subcutaneously |
Sheep goats | 15-25 | Intravenously, intramuscularly or subcutaneously |
Pigs | 15-25 | Intravenously, intramuscularly or subcutaneously |
Piglets | 2-3 | Intramuscularly or subcutaneously |
If necessary, the drug is re-administered in the same doses after 24 hours.
Contraindications:
Hypercalcemia, acidosis, impaired renal function, excessive nervous excitement, ventricular fibrillation, hypersensitivity to the drug.
Warnings:
In one place or n, you can enter no more than 50 ml of the drug. With extreme caution, animals with diseases of the heart and kidneys are used. The introduction should be done slowly to avoid arrhythmias and heart block!
With intramuscular or subcutaneous administration, this risk is much less. Do not use simultaneously with digitalis preparations, as this can cause a violation of the heart function or its blockade. The simultaneous use of calcium and vitamin D or its analogues can lead to hypercalcemia. Throughout the treatment, the meat and milk of animals can be used without restriction by humans.
Storage
A dark place inaccessible to children at temperatures from 40-77F (5 ° C to 25 ° C).
Shelf life – 3 years from the date of manufacture.
Shelf life after the first puncture of the bottle is 28 days.
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