Description
Composition :
1 ml of the preparation contains
active ingredient
Toltrazuril – 50 mg;
PHARMACOLOGICAL PROPERTIES
The drug contains the active substance tetrazuril, a derivative of the triazintrion group, with a wide range of action: Eimeria adenoides, E. alabamensis, E. arloingi, E. bovis, E. brunetti, E. maxima, E. meleagrimitis, E. necatrix, E. scarab, E. tenella, Isospora suis, E. zuernii; and other species at all stages of their intracellular development.
Toltrazuril disrupts intracellular stages of eimerium development, influencing merogony, micro- and macrogametes. It inhibits the fission of the nuclei of emeralds and reduces the activity of mitochondria, which are responsible for respiratory metabolism.
In animals, tetrazuryl is partially metabolized to form sulfonic oxide and sulfon derivatives. Further it is almost completely excreted with faeces in unchanged form or in the form of tetrazuryl sulfone or tetrazuryl sulfon dioxide.
The preparation has no mutagenic, carcinogenic and teratogenic effect.
APPLICATION
Prevention and treatment of young cattle, sheep, goats, pigs, rabbits and poultry (broilers, breeding poultry, repair young chickens, parent and broiler herds, meat turkeys) with eimerioses caused by eimerioses sensitive to tetrazuril.
DOSA:
Calves, lambs, goats.
from 2 weeks of age 0.3 ml to 2.2 lb (1 kg) body weight
One time
Pigs
for 3-5 days lives
0.4 ml of the preparation per 2.2 lb (1 kg) body weight (not less than 0.5 ml and not more than 2 ml per animal)
One time
Rabbits
with 4 weekly age 0.14 ml per 1 kg body weight One time
Poultry 0.5 ml per 1 liter of drinking water (boil out
within 48 hours) or 1.5 ml per liter
drinking water (8 hours each)
Two days
A bird should receive water with the drug as the only source of drinking water. In severe cases, if necessary, the course of treatment is repeated after 5 days.
To achieve the maximum preventive effect and reduce the amount of oocysts in the external environment, in unfavorable for coccidiosis farms the drug is used by animals until the first signs of the disease.
WITHDRAWAL PERIOD
It is allowed to slaughter animals for meat: piglets – in 77 days, calves – in 63 days, rabbits – 70 days, poultry – 14 days after the last application of the drug.
SHELF OF YEARS
From the date of manufacture – 5 years
After the first opening of the bottle – 14 days if it is stored in a dark place at a temperature from 40-77F (5 to 25 ° C).
STORAGE CONDITIONS
Store in a dark, inaccessible place for children at temperatures between 40-77F (5 to 25° C).
Manufacturer: Invesa (Livisto ) / Spain
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