Description
DESCRIPTION
Oily liquid of colorless to light yellow color. Slight amount of sediment is allowed during storage.
COMPOSITION
1 ml of the product contains
the active substance:
Ofloxacin – 100 mg
PHARMACOLOGICAL PROPERTIES
Ofloxacin, an antibiotic of fluoroquinolone group, is the active ingredient of the drug.
Ofloxacin is active against Gram-negative and Gram-positive microorganisms, especially E.coli, Salmonella spp., Shigella spp., Enterobacter spp., Klebsiella spp, Proteus spp., Serratia spp., Camphylobacter spp., Pseudomonas aeruginosa, Yersinia spp., Vibrio spp., Aeromonas spp., Haemophilus spp., also sensitive to the drug: Brucella spp., Chlamydia trachomatis, Staphylococcus spp. (including penicillinase producing and methicillin resistant strains) Mycoplasma spp.
The mechanism of action of the drug is inhibition of bacterial DNA – gyrase (topoisomerase ІІ), thus stopping the process of DNA spiralization and synthesis.
INDICATIONS FOR USE
Pigs, calves and lambs, poultry (broilers and replacement young animals, turkeys), dogs, cats: treatment of animals with respiratory diseases, digestive system, genital system, secondary infections with viral diseases caused by microorganisms sensitive to Ofloxacin.
Treatment of animals and poultry for diseases caused by microorganisms sensitive to Ofloxacin:
Septicemia, pneumonia, bronchitis, rhinitis, sinusitis, bronchopneumonia, gastritis, enteritis, nephritis, mastitis, arthritis and endometritis.
DIRECTIONS FOR USE AND DOSAGES
Orally with drinking water or feed at a dose:
pigs – 0.5 ml of preparation per 22lb (10 kg) of animal body weight;
lambs – 0.5 ml of preparation per 22lb (10 kg) of body weight;
calves – 0.5 ml of the preparation per 22lb (10 kg) of animal body weight;
poultry – 5 ml of the drug per 10 liters of drinking water; depending on severity of the disease, the drug dose can be doubled;
dogs, cats – 0.25 ml of the drug per 22lb (10 kg) of body weight.
The drug shall be administered at intervals of 24 hours, duration of treatment 3-5 days.
CONTRAINDICATIONS
Hypersensitivity to Ofloxacin.
Do not use in animals with severe renal and hepatic dysfunction.
Do not use simultaneously with tetracyclines, macrolides, cyclosporines, chloramphenicols.
Do not use in ruminants with functionally developed pre-stomachs.
Do not use simultaneously with nonsteroidal anti-inflammatory drugs.
Do not use in pregnant bitches and cats, as well as during lactation (for dogs and cats). Administration of the drug in non-productive animals is allowed in cases when sensitivity of microflora to the drug is determined and it is obvious that the effect of administration exceeds possible adverse effects.
Do not apply to laying hens whose eggs are intended for human consumption.
CAUTION
Slaughter of pigs, calves and lambs for meat is allowed 14 days after the last drug administration. Slaughter of poultry for meat is allowed 11 days after the last drug administration.
Meat obtained before the specified period shall be utilized or fed to unproductive animals depending on the conclusion of the veterinarian.
STORAGE
Store away from foodstuffs in a dry, dark place, out of the reach of children at temperatures between 40 and 77F (5°C and 25°C).
SHELF LIFE – 2 years.
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